Benign lymphoepithelial lesion: a less than benign disease
作者:
MICHAEL J. GLEESON,
RODERICK A. CAWSON,
MICHAEL H. BENNETT,
期刊:
Clinical Otolaryngology&Allied Sciences
(WILEY Available online 1986)
卷期:
Volume 11,
issue 1
页码: 47-52
ISSN:0307-7772
年代: 1986
DOI:10.1111/j.1365-2273.1986.tb01992.x
出版商: Blackwell Publishing Ltd
关键词: salivary gland;benign lymphoepithelial lesion;Sjogren's sydrome
数据来源: WILEY
摘要:
Benign lymphoepithelial lesion: a less than benign diseaseThe precise clinical correlate of the benign lymphoepithelial lesion is unclear. Thirty‐six cases of benign lymphoepithelial lesions (BLL), reported to the British Salivary Gland Tumour Panel between 1971 and 1984, have been reviewed. Eighty per cent arose in the parotid gland and 20% were bilateral; 83% were in females and the mean age at presentation was 55.26 years. Only 50% presented with, or developed, symptoms of sicca complex, Sjogren's syndrome or related autoimmune disease. Two cases of BLL had, or went on to develop, extra salivary lymphomas and 5 cases of BLL had lymphomatous change in the initial biopsy. A further case had carcinoma within the benign lymphoepithelial lesion. None of those who developed lymphoma had sicca or Sjogren's syndrome but 3 of them had rheumatoid arthritis. The incidence of lymphomas (salivary or extra‐salivary) in this series is very much higher than that reported in Sjogren's patients and amounted to 20% over
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