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Malignant transformation of eccrine tumors

 

作者: E. Galadari,   A. H. Mehregan,   K. C. Lee,  

 

期刊: Journal of Cutaneous Pathology  (WILEY Available online 1987)
卷期: Volume 14, issue 1  

页码: 15-22

 

ISSN:0303-6987

 

年代: 1987

 

DOI:10.1111/j.1600-0560.1987.tb00122.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

Malignant transformation occurred in pre‐existing sweat gland tumors in 7 patients. Three lesions showed an histologic pattern of eccrine spiradenoma, 2 eccrine poroma, one cylindroma and one papillary eccrine adenoma. Malignant transformation was histologically characterized by the presence of solid tumor areas populated with large cells having irregularly shaped nuclei and mitotic figures. There were multiple foci of squamous metaplasia, areas of loss of basement membrane and invasion of the surrounding connective tissu

 

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