Malignant transformation of eccrine tumors
作者:
E. Galadari,
A. H. Mehregan,
K. C. Lee,
期刊:
Journal of Cutaneous Pathology
(WILEY Available online 1987)
卷期:
Volume 14,
issue 1
页码: 15-22
ISSN:0303-6987
年代: 1987
DOI:10.1111/j.1600-0560.1987.tb00122.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Malignant transformation occurred in pre‐existing sweat gland tumors in 7 patients. Three lesions showed an histologic pattern of eccrine spiradenoma, 2 eccrine poroma, one cylindroma and one papillary eccrine adenoma. Malignant transformation was histologically characterized by the presence of solid tumor areas populated with large cells having irregularly shaped nuclei and mitotic figures. There were multiple foci of squamous metaplasia, areas of loss of basement membrane and invasion of the surrounding connective tissu
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