Serum Levels and Urinary Excretion in Humans of BL-S 578 (Cefadroxil), a New Semisynthetic Cephalosporin
作者:
M. Prenna,
S. Ripa,
期刊:
Chemotherapy
(Karger Available online 1980)
卷期:
Volume 26,
issue 2
页码: 98-102
ISSN:0009-3157
年代: 1980
DOI:10.1159/000237889
出版商: S. Karger AG
关键词: BL-S 578 (cefadroxil);Serum levels;Urinary excretion
数据来源: Karger
摘要:
Single doses of 250 and 500 mg of BL-S 578 (cefadroxil), a new semisynthetic cephalosporin, were orally administered to 13 normal, healthy volunteers and serum levels determined at timed intervals for 7 h. Peak concentration was obtained at 1½ h after administration of 250 mg (8.981 μg/ml) or 500 mg (17.861 μg/ml). Urinary excretion levels within 24 h after ingestion of single doses of 250 and 500 mg of cefadroxil were 89.92 and 86.34%, respective
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