Hereditäres Angioödem: Komplementprofil unter einer Langzeitbehandlung mit Danazol
作者:
B. Wüthrich,
P.J. Grob,
期刊:
Dermatology
(Karger Available online 1980)
卷期:
Volume 160,
issue 3
页码: 167-174
ISSN:1018-8665
年代: 1980
DOI:10.1159/000250491
出版商: S. Karger AG
关键词: Hereditary angio-oedema;C1 esterase inhibitor;C4 Danazol
数据来源: Karger
摘要:
A mother and her son are described who both suffer from hereditary angiooedema. Both were treated with Danazol, a synthetic derivative of ethisterone. The prophylactic clinical effect seemed obvious, and also the serum concentration of the complement component C4, which had regularly been lower before treatment, became normal. However, no change of the serum concentration of the C1 esterase inhibitor could be demonstrated; this is in contrast to observations of other authors.
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