Visual Involvement in Friedreich’s Ataxia: PERG and VEP Study
作者:
F. Pinto,
A. Amantini,
G. de Scisciolo,
V. Scaioli,
L. Guidi,
R. Frosini,
期刊:
European Neurology
(Karger Available online 1988)
卷期:
Volume 28,
issue 5
页码: 246-251
ISSN:0014-3022
年代: 1988
DOI:10.1159/000116277
出版商: S. Karger AG
关键词: Friedreich’s ataxia;Pattern electroretinogram;Visual evoked potential;Red-free light retinography
数据来源: Karger
摘要:
Neuro-ophthalmological assessment, including red-free light retinography, in conjunction with simultaneous visual evoked potential (VEP) and pattern electroretinogram (PERG) recordings were performed in 10 Friedreich’s ataxia patients: 9 patients showed marked VEP abnormalities. Moderate PERG amplitude reduction, with normal latencies, was related to mild and scattered fiber loss revealed by red-free light retinography. The initial part of the visual pathways does not seem to be the main site of electrophysiological abnormalities as demonstrated by the greater extent and relative independence of VEP versus PERG alterations. Primary axonal degeneration of the optic nerve and tracts cannot account for all features of VEP abnormalities, thus implying some dysfunction in succeeding visual structures as wel
点击下载:
PDF
(1117KB)
返 回