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Lack of robustness in time-space disease clustering

 

作者: Paula K. Roberson,   Lloyd Fisher,  

 

期刊: Communications in Statistics - Simulation and Computation  (Taylor Available online 1983)
卷期: Volume 12, issue 1  

页码: 11-22

 

ISSN:0361-0918

 

年代: 1983

 

DOI:10.1080/03610918308812297

 

出版商: Marcel Dekker, Inc.

 

关键词: disease models;epidemiology

 

数据来源: Taylor

 

摘要:

The Knox and Mantel procedures of time-space disease clustering are shown to be nonrobust in certain situations. The effect of selecting the necessary constants by a trial-and-error approach drastically alters the nominal significance level. When the population is shifting over time or when the detection rate of the disease is not constant, this artificially induced space-time clustering can increase the probability of rejection to two or more times the nominal significance level.

 

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