Antimicrobial Spectrum of Triclosan, a Broad-Spectrum Antimicrobial Agent for Topical Application
作者:
J. Regös,
O. Zak,
R. Solf,
W.A. Vischer,
E.G. Weirich,
期刊:
Dermatology
(Karger Available online 1979)
卷期:
Volume 158,
issue 1
页码: 72-79
ISSN:1018-8665
年代: 1979
DOI:10.1159/000250746
出版商: S. Karger AG
关键词: Topical antimicrobials;Microbiological activity evaluations;Triclosan
数据来源: Karger
摘要:
The antimicrobial activity of 5-chloro-2(2,4-dichlorophenoxy) phenol (triclosan, one of the active ingredients of Logamel®, Ciba-Geigy) was compared in vitro with that of other antimicrobials exclusively or occasionally used as topical agents in dermatology: hexachlorophene, clioquinol, chlorquinaldol. gentamicin, neomycin, nystatin, econazole, clotrimazole and salicylic acid. Upon determination of the MICs for 53 strains of aerobic and anaerobic bacteria, yeasts and fungi, triclosan was found to display a high degree of activity against most of the test organisms and to have the broadest spectrum of chemotherapeutically significant antimicrobial activity of the substances tested
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