Genetic Polymorphism of Glycine-Rich Beta-Glycoprotein in the Italian Population
作者:
R. Scherz,
R. Pflugshaupt,
R. Bütler,
F. Peyretti,
期刊:
Human Heredity
(Karger Available online 1982)
卷期:
Volume 32,
issue 1
页码: 11-14
ISSN:0001-5652
年代: 1982
DOI:10.1159/000153253
出版商: S. Karger AG
关键词: Glycyne-richβ-glycoprotein;Properdin factor B;C3 proactivator;Gene frequencies;Italian population
数据来源: Karger
摘要:
Genetic polymorphism of glycine-rich β-glycoprotein (GBG) was studied in populations from northern and southern Italy, respectively. Gene frequencies were as follows: northern Italy (n = 431): GbS = 0.7675, GbF = 0.2049, GbS0.7 = 0.0127, GbF1 = 0.0139; southern Italy (n = 161): GbS = 0.7050, GbF = 0.2360, GbS0.7 = 0.0373, GbF1 = 0.0217. Comparison of these two populations with the Swiss population revealed a significant drift in gene frequencies from north to south. A new GBG phenotype, supposedly heterozygous, with a slow migrating F band and a regular S band in agarose electrophoresis was observed
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