Colony‐Stimulating Factors: Clinical Applications
作者:
Susan Blackwell,
Jeffrey Crawford,
期刊:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
(WILEY Available online 1992)
卷期:
Volume 12,
issue 2P2
页码: 20-31
ISSN:0277-0008
年代: 1992
DOI:10.1002/j.1875-9114.1992.tb02679.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Recombinant human colony‐stimulating factors (CSFs) have potential for wide use in the areas of oncology and infectious disease. Granulocyte CSF and granulocyte‐macrophage CSF currently are approved for use in the treatment of neutropenia associated with standard‐dose cancer chemotherapy and bone marrow transplantation, respectively. Other settings in which these agents have shown promise are dose‐intensive chemotherapy, enhancement of progenitor cell support, primary and acquired neutropenias, myelodysplasia, aplastic anemia, and cytopenias associated with human immunodeficiency virus infection or myelosuppressive therapies for such infection or related conditions. Clinical findings in these areas are encouraging, and potential exists for additional applications of t
点击下载:
PDF
(1361KB)
返 回