Phospholipid transfer protein in lipid metabolism
作者:
Jarkko Huuskonen,
Christian Ehnholm,
期刊:
Current Opinion in Lipidology
(OVID Available online 2000)
卷期:
Volume 11,
issue 3
页码: 285-289
ISSN:0957-9672
年代: 2000
出版商: OVID
数据来源: OVID
摘要:
Phospholipid transfer protein (PLTP) is one of the main modulators of plasma HDL size and composition. The publications discussed in the present review have substantially increased our knowledge on the physiological importance of PLTP-mediated phospholipid transfer, especially between triglyceride-rich lipoproteins and HDL. Furthermore, novel data have provided clues about the transfer mechanism, and evidence for the direct involvement of PLTP in atheroprotection has recently been presented. The development of assays for PLTP mass determination has offered new tools for the elucidation of the physiological role of PLTP.
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