Zinc intake, zinc status and growth in a longitudinal study of healthy Danish infants
作者:
KF Michaelsen,
G. Samuelson,
TW Graham,
B. Lönnerdal,
期刊:
Acta Paediatrica
(WILEY Available online 1994)
卷期:
Volume 83,
issue 11
页码: 1115-1121
ISSN:0803-5253
年代: 1994
DOI:10.1111/j.1651-2227.1994.tb18262.x
出版商: Blackwell Publishing Ltd
关键词: Breast feeding;erythrocyte metallothionein;infant nutrition;weaning foods;zinc deficiency
数据来源: WILEY
摘要:
Mild, growth‐limiting zinc deficiency might be prevalent in otherwise healthy infants according to recent studies. We examined zinc intake and status in 91 healthy term infants from birth to 12 months, as part of the Copenhagen Cohort Study on Infant Nutrition and Growth. Zinc intake was recorded monthly and the amount of zinc absorbed was estimated. These estimates were below recently published FAO/WHO/IAEA values for basal requirements in 68%, 62% and 14% of the infants at 2, 4 and 9 months of age, respectively. Serum zinc decreased significantly (p<0.01) from 10.6 μmol/l at 6 months to 8.4μmol/l at 9 months of age (normal range 10–18 μmol/l). Erythrocyte metallothionein values, a tentative indicator of long‐term zinc status, decreased significantly from 2 to 6 months (p<0.001) and from 6 to 9 months (p<0.01). Serum zinc at 9 months was positively associated with growth velocity during the period from 6 to 9 months (weight:p= 0.05; knee‐heel length:p= 0.002). The results provide descriptive data on zinc intake and zinc status in healthy Danish infants. Although some of our data suggest suboptimal zinc status during late infancy, evidence for this can only be obtained through a randomized interven
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