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The rat MIS1/Pvt-1locus is syntenic with MYC on chromosome 7

 

作者: S. Ingvarsson,   Z. Wirschubsky,   J. Szpirer,   G. Levan,   G. Klein,   J. Sümegi,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1987）
卷期: Volume 45, issue 3-4  

页码: 174-176

 

ISSN:1424-8581

 

年代: 1987

 

DOI:10.1159/000132450

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

Mouse Pvt-1 and rat MISl are frequent proviral integration sites in retrovirally induced lymphomas. The Pvt-1 locus is also involved in mouse plasmacytoma (6;15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-1/MISl locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protoon-cogene and the MIS1/Pvt-1 locus.

 

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