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The Value of Flunarizine in the Treatment of Tinnitus

 

作者: Jan H. Hulshof,   Pieter Vermeij,  

 

期刊: ORL  (Karger Available online 1986)
卷期: Volume 48, issue 1  

页码: 33-36

 

ISSN:0301-1569

 

年代: 1986

 

DOI:10.1159/000275839

 

出版商: S. Karger AG

 

关键词: Tinnitus;Flunarizine;Double-blind trial

 

数据来源: Karger

 

摘要:

The suppressive effect of flunarizine on tinnitus was assessed in a double-blind trial in 50 patients with tinnitus due to various causes. The duration of the study was 6 weeks. Serum levels of the drug were determined. The patient’s subjective assessment of the effect was taken as criterion for the evaluation; objective tests were found to be unsuitable for this purpose. Ten of the patients suffered from dizziness as a secondary complaint. For the group as a whole, there was no difference between flunarizine and the placebo with respect to the effect on tinnitus, but in the 10 patients with dizziness as well there was a significant difference in favor of the drug. Conclusions cannot be drawn as to the reason for this divergence, because the number of patients was too smal

 

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