Machine-mediated interviewing is a technique of psychiatric interviewing in which patient and interviewer communicate by means of remotely located teletypes. Messages are transmitted from one teletype to another by means of a computer. Advantages of non-nonverbal communication in the study of the psychiatric interview and in the development of a computer program designed to conduct psychiatric interviews are discussed. Excerpts from representative interviews with different patients are reproduced; seven of the interviews were conducted with a hospitalized mute patient who, after the fifth interview, began to use spoken language for communication. This novel technique is suggested for patients who are unable to participate in the usualvis-à-visinterview.