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Pharmacokinetics of Azlocillin in Neonates

 

作者: U. Sitka,   L. Weingärtner,   R. Patsch,   I. Richter,  

 

期刊: Chemotherapy  （Karger Available online 1980）
卷期: Volume 26, issue 3  

页码: 171-176

 

ISSN:0009-3157

 

年代: 1980

 

DOI:10.1159/000237901

 

出版商: S. Karger AG

 

关键词: Azlocillin;Pharmacokinetics;Neonatal period

 

数据来源: Karger

 

摘要:

The pharmacokinetics of the acylureido-penicillin, azlocillin, were studied after intravenous or intramuscular injections in 53 premature and full-term infants with infections. Effective concentrations were achieved in premature babies after doses of 50 mg/kg every 12 h and in full-term infants with 100 mg/kg every 12 h. No untoward effects of azlocillin were observed. On the basis of these studies, a dosage schedule for azlocillin has been established.

 

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