Rickets in extremely low birthweight infants
作者:
GEOFFREY J. CLEGHORN,
DAVID I. TUDEHOPE,
JOHN P. MASEL,
期刊:
Journal of Paediatrics and Child Health
(WILEY Available online 1981)
卷期:
Volume 17,
issue 4
页码: 285-289
ISSN:1034-4810
年代: 1981
DOI:10.1111/j.1440-1754.1981.tb01961.x
出版商: Blackwell Publishing Ltd
关键词: Extremely low birth weight infants;rickets of prematurity;radiological stages of rickets;alkaline phosphatase
数据来源: WILEY
摘要:
ABSTRACT.The effects of increasing the concentration of supplemental vitamin D was studied in two groups of ELBW infants (babies with a birth weight less than 1000 g) during the periods of July 1977 to December 1979 and throughout 1980. There were 21 ELBW infants in the first study period, with 7 infants developing active or Stage III rickets. A prospective study of ELBW infants during 1980 revealed 3 infants out of the 12 studied developing active or Stage III rickets. A new radiological classification for rickets of prematurity, Stage I to IV, is presented. Serial serum alkaline phosphatase levels were then compared with these radiological stages and a serial ALP of 500IU/l was found to be statistically significant in the biochemical diagnosis of rickets. As a result of our findings, we suggest that all ELBW should be supplemented with at least 800 IU of vitamin D daily.
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