Effects of Fenugreek Seeds on Endocrine Pancreatic Secretions in Dogs
作者:
Gé;rard Ribes,
Yves Sauvaire,
Jean-Claude Baccou,
Guy Valette,
Dominique Chenon,
Elisabeth Trimble,
Marie-Madeleine Loubatières-Mariani,
期刊:
Annals of Nutrition and Metabolism
(Karger Available online 1984)
卷期:
Volume 28,
issue 1
页码: 37-43
ISSN:0250-6807
年代: 1984
DOI:10.1159/000176780
出版商: S. Karger AG
关键词: Fenugreek;Blood glucose;Endocrine pancreas;Dog
数据来源: Karger
摘要:
The components of fenugreek seeds were separated and analyzed to determine which fraction of the seed had hypoglycemic activity. These fractions were administered orally to normal or diabetic dogs for 8 days. The effect on blood glucose and pancreatic hormones was studied in normal dogs. The lipid extract had no effect; the defatted fraction (50.2% fibers: gum 17.7%, hemicellulose 22%, cellulose 8.3%, lignin 2.2%) lowered basal blood glucose level, plasma glucagon and somatostatin levels and reduced the orally induced hyperglycemia. The addition of this fraction to the insulin treatment resulted in a decrease of hyperglycemia and glycosuria in diabetic dogs. The results indicate that the defatted part is responsible for the antidiabetic action. However, the present study does not permit one to know whether the effects are caused by an unknown pharmacological compound or by the gastrointestinal action of fibers.
点击下载:
PDF
(1029KB)
返 回