Usefulness of platelet‐derived growth factor as a prognostic factor in pulmonary adenocarcinoma
作者:
Iwao Takanami,
Yasuki Yamamoto,
Susumu Kodaira,
Tetsuo Imamura,
期刊:
Journal of Surgical Oncology
(WILEY Available online 1995)
卷期:
Volume 58,
issue 1
页码: 40-43
ISSN:0022-4790
年代: 1995
DOI:10.1002/jso.2930580109
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: immunohistochemistry;proliferation;prognosis
数据来源: WILEY
摘要:
AbstractPlatelet‐derived growth factor (PDGF) in the resected pulmonary adenocarcinoma tissue of 88 patients was detected immunohistochemically by the avidin‐biotin‐peroxidase technique to determine whether or not it is a prognostic parameter. The 88 patients were divided into PDGF (‐) and PDGF (+) groups according to the stainability of the factor. The PDGF (‐) group included 39 patients and the PDGF (+) group 49. The 5‐year survival rate was 53% for the PDGF (‐) group and 17% for the PDGF (+) group (P<0.01). These findings indicate that the stainability of PDGF can be a prognostic parameter for pulmonary adenocarcinoma. © 1995 W
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