Distention of the Uterus Activates Its Multiple Pacemakers and Induces Their Coordination
作者:
Yukio Manabe,
Morihiko Sakaguchi,
Takahide Mori,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1994)
卷期:
Volume 38,
issue 3
页码: 163-168
ISSN:0378-7346
年代: 1994
DOI:10.1159/000292471
出版商: S. Karger AG
关键词: Uterine distention;Uterine activity;Labor induction;Pacemaker
数据来源: Karger
摘要:
In the pregnant human uterus, pacemaker activities and their coordination processes were studied in labor induced by uterine distention. Electrical and mechanical activities of the uterus were simultaneously recorded in 6 midtrimester (normal, n = 4; fetal death, n = 2) and 8 term (normal, n = 7; fetal death, n = 1) patients. Initially, frequent and sporadical spike discharges which did not synchronize with low magnitude and irregular mechanical activities were noted. With time, synchronization of both activities developed. These findings were noted regardless of the gestational stage of the patient and fetal viability. The patterns of development and decreases in mechanical and electrical activities, together with their synchronization patterns, were positively and negatively controlled by uterine distention and its suspension, respectively. These results suggest that the uterus has multiple pacemakers in various locations, and uterine distention works as a trigger for the elevation of excitability and for coordinated and orthodromic activities.
点击下载:
PDF
(2902KB)
返 回