Genetics of Lattice Degeneration of the Retina
作者:
Fumiyo Murakami,
Norio Ohba,
期刊:
Ophthalmologica
(Karger Available online 1982)
卷期:
Volume 185,
issue 3
页码: 136-140
ISSN:0030-3755
年代: 1982
DOI:10.1159/000309235
出版商: S. Karger AG
关键词: Lattice degeneration;Genetics;Prevalence;First-degree relatives;Poly-genic model
数据来源: Karger
摘要:
First-degree relatives of proband patients with lattice degeneration of the retina revealed a significantly higher prevalence of the disease than the prevalence in the general population: the former had the disease about three times as frequently as the latter. The observed data were analyzed in terms of their accordance with recognized genetic models. The inheritance pattern did not fit well to a monogenic mode of inheritance, and it was hypothesized that a polygenic or multifactorial mode of inheritance is the most likely for lattice degeneration of the retina.
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