Somatic Mutation Affecting the Rhesus and Duffy Blood Group Systems
作者:
W. J. Jenkins,
W. L. Marsh,
期刊:
Transfusion
(WILEY Available online 1965)
卷期:
Volume 5,
issue 1
页码: 6-10
ISSN:0041-1132
年代: 1965
DOI:10.1111/j.1537-2995.1965.tb01129.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
A normal blood donor has been encountered whose red cell grouping tests showed a mixed cell population of CDe/cde, Fy(a+) and cde/cde, Fy(a—) cells. A family study revealed that the cde/cde, Fy(a—) cell population could not have arisen through a normal genetic pathway and reasons are given for suggesting that a gene mutation had occurred. As both Rhesus and Duffy genes are affected, it is concluded that the mutation has modified a common gene involved at some stage in the development of both blood group antig
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