L-Asparaginase Treatment of Acute Myeloblastic Leukemia
作者:
H.H. Hansen,
G.P. Canellos,
期刊:
Oncology
(Karger Available online 1970)
卷期:
Volume 24,
issue 5
页码: 349-357
ISSN:0030-2414
年代: 1970
DOI:10.1159/000224536
出版商: S. Karger AG
数据来源: Karger
摘要:
Nine adults with acute myeloblastic leukemia were treated with L-asparaginase, a new anti-neoplastic agent. One of these patients achieved a complete remission. This case is presented in detail including serial determinations of serum L-asparaginase levels during the treatment. The mechanism of action, toxicology and the present status of the effectiveness of L-asparaginase in acute leukemia are presented. Optimal dose schedule and possible future role of L-asparaginase in the treatment of leukemia is discussed.
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