Mortality supposedly due to intoxication by pyrrolizidine alkaloids fromheliotropium indicumin a horse population in costa rica: A case report
作者:
P.R. van Weeren,
J.A. Morales,
L.L. Rodriguez,
H. Cedeño,
J. Villalobos,
L.J. Poveda,
期刊:
Veterinary Quarterly
(Taylor Available online 1999)
卷期:
Volume 21,
issue 2
页码: 59-62
ISSN:0165-2176
年代: 1999
DOI:10.1080/01652176.1999.9694993
出版商: Taylor & Francis Group
关键词: Horse;hepatoencephalopathy;pyrrolizidine alkaloids;neurological signs;VEE
数据来源: Taylor
摘要:
This article describes a case of massive mortality among horses which was probably due to intoxication by pyrrolizidine alkaloids fromHeliotropium indicum. Over 4 years more than 75% of a population of about 110 horses on a farm in Costa Rica died after showing nervous neurological symptoms. Two clinical manifestations were encountered, an acute and a chronic one, both with a fatal outcome. Pathological findings in 2 horses coincided with those reported in the literature for intoxication by pyrrolizidine alkaloids and were not specific for VEE. However Venezuelan equine encephalitis (VEE) was the main differential diagnosis and could not completely be excluded because this disease was endemic in the region and VEE titres were found to be high. Taxonomic and toxicological investigations implicatedHeliotropium indicumas the most probable principal cause of the intoxication.
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