Estriol and Cholic Acid in Maternal Serum in Induced Labor
作者:
K. Bremme,
P. Eneroth,
K. Samuelson,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1984)
卷期:
Volume 17,
issue 3
页码: 120-126
ISSN:0378-7346
年代: 1984
DOI:10.1159/000299134
出版商: S. Karger AG
关键词: Total estriol;Nonconjugated estriol;Cholic acid;Induced labor;Maternal blood;Umbilical blood
数据来源: Karger
摘要:
Prostaglandin E2 (PGE2), but not oxytocin, treatment to induce parturition brought about an increase (p < 0.001) in maternal serum levels of total estrogens (conjugated and nonconjugated estriol). There was no increase in nonconjugated estriol. To explore if the changes were related to an altered enterohepatic circulation, cholic acid assay in maternal serum was used. There were no changes in cholic acid which parallelled those in total estrogens. It is concluded that PGE2 does not appear to affect enterohepatic circulation of steroids, and it is suggested that the increase in total estrogens may be caused by changes in the kidney excretion of estriol.
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