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A Plasma Factor Inhibiting Prostacyclin-Like Activity in Thrombotic Thrombocytopenic Purpura

 

作者: S.J. Machin,   B.A. McVerry,   H. Parry,   W.J.W. Marrow,  

 

期刊: Acta Haematologica  （Karger Available online 1982）
卷期: Volume 67, issue 1  

页码: 8-12

 

ISSN:0001-5792

 

年代: 1982

 

DOI:10.1159/000207018

 

出版商: S. Karger AG

 

关键词: Inhibitory plasma factor;Prostacyclin;TTP

 

数据来源: Karger

 

摘要:

The plasma from a patient with thrombotic thrombocytopenic purpura contained a low molecular weight dialysable factor which inhibited the synthesis and release or activity of prostacyclin-like activity from vascular tissue. This factor was not an immunoglobulin or complement component. Following fresh plasma infusions the ability of the patient’s plasma to stimulate the release of prostacyclin-like activity returned but no clinical improvement occurre

 

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