Bone Marrow Transplantation for Hepatitis-Associated Aplastic Anemia
作者:
Seiji Kojima,
Kohji Matsuyama,
Yoshihisa Kodera,
期刊:
Acta Haematologica
(Karger Available online 1988)
卷期:
Volume 79,
issue 1
页码: 7-11
ISSN:0001-5792
年代: 1988
DOI:10.1159/000205682
出版商: S. Karger AG
关键词: Aplastic anemia;Bone marrow transplantation;Hepatitis
数据来源: Karger
摘要:
Five patients with hepatitis-associated aplastic anemia were transplanted with HLA-identical, mixed lymphocyte culture-compatible sibling marrow. One patient who had suffered from severe chronic graft-versus-host disease died from intracranial bleeding at 42 months following the transplant. The other four patients are surviving from 15 to 54 months after transplant with a median follow-up of 21 months. Previous hepatic damage from viral hepatitis and liver function abnormalities existing at the time of grafting do not appear to increase the risk of hepatic venocclusive disease or the side effects of ciclosporin in patients with hepatitis-associated aplastic anemia.
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