Nature of the Blood Coagulation Mechanisms in SPCA Plasma
作者:
Walter Seegers,
Norma Alkjaersig,
期刊:
Circulation Research
(OVID Available online 1955)
卷期:
Volume 3,
issue 5
页码: 514-518
ISSN:0009-7330
年代: 1955
出版商: OVID
数据来源: OVID
摘要:
Derivatives of purified prothrombin and substances required for the formation of a derivative have been studied in connection with SPCA deficient plasma. The deficiency can be corrected in vitro with prothrombin derivatives. It is concluded that the SPCA patient cannot convert prothrombin to autoprothrombin and thrombin in the same way as a normal individual, and that the precursor of SPCA is prothrombin.
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