This is a study of the psychology of college students who use LSD and other psychedelics regularly.Fifteen students who used psychedelic drugs regularly (most frequently LSD) were studied in detail using psychoanalytic interviewing techniques. Short term therapy was administered when indicated. Psychological tests (Wechsler Adult Intelligence Scale, Rorschach, Thematic Apperception Test, Sentence Completion, Figure Drawing, and Word Association) were performed and used as an independent check on the data derived from the interviews. Also studied were an equal number of students who had used LSD or other psychedelic drugs only occasionally.While there are students who use almost any and all drugs, most have particular drugs of choice that produce in them the particular psychological and pharmacological effects they want. Over and over regular LSD users among college students speak of being cut off from their inner feelings, of having been helped, or of hoping they will be helped to overcome their sense of lifelessness by LSD. This paper explores and illustrates with 3 cases the sources of the emotional constriction of which these students complain, their psychodynamic response to the impact of LSD, and the intimate relationship between the good and bad trip.