Three cases of Acute Diffuse Lymphocytic Meningo‐encephalitis
作者:
Hiroshi ISHINO,
Mitsuo MOTOIKE,
Teruo OKUMA,
Takashi Mil,
Jun TATEISHI,
Yasuaki HAYASHI,
Kazuhiko ISHIGAKI,
Norikuni YAMANE,
Susumu HIGASHI,
Shigeru INOUE,
期刊:
Psychiatry and Clinical Neurosciences
(WILEY Available online 1969)
卷期:
Volume 23,
issue 1
页码: 25-32
ISSN:1323-1316
年代: 1969
DOI:10.1111/j.1440-1819.1969.tb01439.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SummaryClinical and pathological descriptions were made on the three cases of acute diffuse lymphocytic meningo‐encephalitis.Clinical pictures of all cases were super‐posable in almost all respects: acute onset of the illness, meningeal symptom such as headache and vomiting, convulsions, con‐fusional state and psychomotor restlessness which necessitated all patients being admitted to the psychiatric clinic. Pressure of CSF was elevated in two cases and pleo‐cytosis was noted. After the clinical course of about 4 weeks the patients died.Morphological picture of three cases was very slight in comparison with severe clinical symptoms and consisted of perivascular lymphocytic infiltration in the frontal, temporal and parietal cortex and a very slight microglial response as well as the involvement of meninges. In Case 1 glial nodules were noted in the midbrain and pons. These changes were milder in Case 2 and Case 3 than in Case 1.The diagnostic problems and the anatomical findings were discussed and it was suggested that our three cases were primary encep
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