Positron emission tomography and radiation oncology
作者:
Gary D. Fullerton, PhD,
Peter Fox, MD,
William T. Phillips, MD,
期刊:
AIP Conference Proceedings
(AIP Available online 1901)
卷期:
Volume 593,
issue 1
页码: 49-54
ISSN:0094-243X
年代: 1901
DOI:10.1063/1.1420465
出版商: AIP
数据来源: AIP
摘要:
Medical physics research is providing new avenues for addressing the fundamental problem of radiation therapy-how to provide a tumor-killing dose while reducing the dose to a non-lethal level for critical organs in adjacent portions of the patient anatomy. This talk reviews the revolutionary impact of Positron Emission Tomography on the practice of radiation oncology. The concepts of PET imaging and the development of “tumor” imaging methods using18F-DGflouro-deoxyglucose are presented to provide the foundation for contemporary research and application to therapy. PET imaging influences radiation therapy decisions in multiple ways. Imaging of occult but viable tumor metastases eliminates misguided therapy attempts. The ability to distinguish viable tumor from scar tissue and necroses allows reduction of treatment portals and more selective treatments. Much research remains before the clinical benefits of these advances are fully realized. ©2001 American Institute of Physics.
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