Antibiotic Sensitivity of Gonococcal Strains Isolated from Patients in Basel and Environs
作者:
J. Füllhaas,
W.A. Vischer,
P. Brügger,
T. Rufli,
期刊:
Dermatology
(Karger Available online 1979)
卷期:
Volume 158,
issue 4
页码: 249-256
ISSN:1018-8665
年代: 1979
DOI:10.1159/000250765
出版商: S. Karger AG
关键词: Neisseria gonorrhoeae;Penicillin;Spectinomycin;Doxycycline;Thiamphenicol;Rifampicin;Sensitivity
数据来源: Karger
摘要:
During the first 4 months of 1977, 95 different strains of gonococcus were isolated in the out-patient department of the Dermatology Clinic of the University of Basel. These were systemically tested for sensitivity to penicillin G, spectinomycin, thiamphenicol, doxycycline and rifampicin. The MIC values and the diameter of the zones of inhibition were determined. Tests for β-lactamase production were made. A correlation in the degree of sensitivity was observed between the following antibiotics: penicillin G/rifampicin; penicillin G/thiamphenicol; penicillin G/doxycycline; thiamphenicol/doxycycline; thiamphenicol/rifampicin; doxycycline/rifampicin. The size of the inoculum had little influence on the activity of the substances, except for that of penicillin G against the β-lactamase-positive reference strains. No β-lactamase-producing strains were detected amongst the clinical isolates. In the case of penicillin G, there was a correlation between the minimum inhibitory concentration and the inhibition-zone diamet
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