AbstractIn its attempt to achieve acknowledgement and support as a true science and academic discipline eighteenth‐century chemistry experienced that the traditional distinction between theory and practice, respectively between science and art, was an incriminating heritage and did not longer conform to the way chemists saw themselves. In order to substitute the former, socially judging classification into theoretical science and practical art, J. G. Wallerius from Uppsala coined the termpure and applied chemistryin 1751. The idea behind this new conception was that it ought to be chemistry's research aim and not the kind of work, be it manual or intellectual, which was to decide about its branches and their dignity. The change in orientation which took place during the eighteenth century, and which is symbolized by the new dichotomy “pure and applied”, led towards a revaluation of the utilitarian aspects of chemistry. Its historical roots reach back to a long and fruitful cooperation of, and interaction between chemistry and economy, which was reinforced by the Stahlian tradition in Germany and Scandinavia. Subsequently, it was its strong economic bias that helped chemistry to become institutionalized and accepted as an academic discipline distinct from the medico‐pharmaceutical profession. The analysis of this change of attitudes, behaviour and institutional pattern suggests that, at least during the period of institutionalization of this particular discipline, social structures and the intrinsic scientific contents are so tightly interrelated, that any division into “internal”, cognitive developments (facts, theory and subject‐matter) and “external” conditions (social context and stategies of institutionalization) would be artificial, since they both constitute the scientific community as a context of argumen