ABSTRACTComputer analysis of EEG data, recorded under both resting and work conditions following smoking, was compared to the appropriate control data in 6 male subjects. Following digitizing, a Power Spectral Analysis was performed which revealed significant reductions in the peak alpha frequency component up to 20 min following smoking, during a visual task. Eyes open resting data showed a similar but not significant loss, after 8 min. No indications of increased fast activity were found. These results were related to comparable work on animals and humans. A suggestion was made as to the relevance of these changes.