Determination of serum oxalate using peroxyoxalate chemiluminescence of free oxalic acid
作者:
S. Albrecht,
H. Hornak,
T. Freidt,
W. D. Böhm,
K. Weis,
A. Reinschke,
期刊:
Journal of Bioluminescence and Chemiluminescence
(WILEY Available online 1993)
卷期:
Volume 8,
issue 1
页码: 21-24
ISSN:0884-3996
年代: 1993
DOI:10.1002/bio.1170080105
出版商: John Wiley&Sons, Ltd.
关键词: Chemiluminescence;haemodialysis;oxalate determination;urolithiasis;peroxyoxalate chemiluminescence;ascorbic acid
数据来源: WILEY
摘要:
AbstractWe describe a new sensitive and specific method for determination of oxalate in human serum. By using the chemiluminescence decay of monoperoxyoxalic acid very low concentrations of oxalate (200 nmol/L) can be determined. The mean serum oxalate level in apparently healthy controls was 14.5 ± 8.5 m̈mol/L. Supplementation of ascorbic acid leads to an increase in serum oxalate level. While serum oxalate concentrations of calcium oxalate stone formers (x = 16.4 ± 9.8 m̈mol/L) are not significantly different from the control group, an extreme increase of serum oxalate is evident in haemodialysis patients. The serum oxalate concentration decreased during dialysis treatment from 141.4 ± 32.1 m̈mol/L to 36.4 ± 12.7 m
点击下载:
PDF
(281KB)
返 回