Paraneoplastic Hypercalcemia in Endometrial Carcinoma
作者:
Nurith Hiller,
Moshe Sonnenblick,
Chaim Hershko,
期刊:
Oncology
(Karger Available online 1989)
卷期:
Volume 46,
issue 1
页码: 45-48
ISSN:0030-2414
年代: 1989
DOI:10.1159/000226679
出版商: S. Karger AG
关键词: Uterus;Hypercalcemia;Endometrial carcinoma;Paraneoplastic syndrome
数据来源: Karger
摘要:
Humoral hypercalcemic syndrome associated with tumors of the female reproductive system is believed to be uncommon, and only 27 such cases have been identified prior to 1980. We describe 2 patients with humoral hypercalcemia in clear cell adenocarcinoma of the uterus, and review the literature on previously published cases. Both our patients fulfilled the criteria for humoral hypercalcemic syndrome, namely: hypercalcemia without bone metastases ranging from 12.8 to 14.1 mg/dl in the presence of normal serum parathyroid hormone levels, reduced tubular reabsorption of phosphate, and reduced serum albumin. We propose that humoral hypercalcemia is perhaps not a rare complication of uterine malignancy and, that increased awareness may result in early diagnosis of this important metabolic problem.
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