首页   按字顺浏览 期刊浏览 卷期浏览 Effects of Cimetidine and Poldine on Nocturnal Gastric Secretion in Duodenal Ulcer
Effects of Cimetidine and Poldine on Nocturnal Gastric Secretion in Duodenal Ulcer

 

作者: J.H.B. Saunders,   J.M. Cargill,   K.G. Wormsley,  

 

期刊: Digestion  （Karger Available online 1977）
卷期: Volume 15, issue 5  

页码: 452-456

 

ISSN:0012-2823

 

年代: 1977

 

DOI:10.1159/000198033

 

出版商: S. Karger AG

 

关键词: Anticholinergics;Duodenal ulcer;Histamine;H2-receptor antagonists;Gastric acidity determination;Gastric juice;Pepsin

 

数据来源: Karger

 

摘要:

Cimetidine inhibited nocturnal secretion of acid but only slightly inhibited the nocturnal secretion of pepsin in patients with duodenal ulcer. Administration of cimetidine (200 or 400 mg), together with an anticholinergic drug (poldine), augmented the inhibition of the nocturnal secretion of acid and of pepsin. The combination of an H2-receptor-blocking drug with an anticholinergic drug will have therapeutic application in the management of duodenal ulceration.

 

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