The Effect of the Alkaline Tide on Serum-Ionized Calcium Concentration in Man
作者:
W. Hughes,
S. Cohen,
D. Arvan,
B. Seamonds,
期刊:
Digestion
(Karger Available online 1977)
卷期:
Volume 15,
issue 3
页码: 175-181
ISSN:0012-2823
年代: 1977
DOI:10.1159/000198001
出版商: S. Karger AG
关键词: Acid-base equilibrium;Alkalosis;Calcium;Gastric juice;Gastrin;Histamine
数据来源: Karger
摘要:
The effect of the gastric alkaline tide on serum-ionized calcium levels was determined in human subjects. Gastric acid seretion was stimulated by a standard steak meal, human synthetic gastrin, and betazole hydrochloride. Ionized calcium levels fell to a similar extent after each stimulus. The mean decrease in calcium ion concentration in all experiments was 5.4 % of the basal concentration. The fall in serum calcium ion concentration was highly correlated with the rise in serum pH. We speculate that increased formation of calcium bicarbonate complex in the serum as well as increased binding of ionized calcium by serum protein accounts for the surprisingly large effect of the alkaline tide on serum-ionized calcium levels.
点击下载:
PDF
(691KB)
返 回