Effect of Hyperprolactinemia on Pituitary-Adrenal Function
作者:
Jerome M. Feldman,
James W. Plonk,
期刊:
Hormone Research in Paediatrics
(Karger Available online 1978)
卷期:
Volume 9,
issue 1
页码: 1-11
ISSN:1663-2818
年代: 1978
DOI:10.1159/000178891
出版商: S. Karger AG
关键词: Prolactin;Pituitary-adrenal axis;Metyrapone;Adrenocorticotrophic hormone;Pituitary tumor
数据来源: Karger
摘要:
Three patients with hyperprolactinemia (2 with pituitary tumors and 1 with a hypothalamic disturbance) underwent evaluation of their hypothalamic-pituitary-adrenal axis using ACTH, metyrapone and in one case repetitive insuün tolerance tests. With the exception of a suggestion of a slight increase in adrenal responsiveness to pharmacological doses of ACTH in one of the patients, there was no alteration in the adrenal responsiveness of the 3 patients evaluated. We conclude that hyperprolactinemia probably does not systematically modify the responsiveness of the hypothalamic-pituitary-adrenal axis
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