PRESENSITIZATION TO TRANSPLANTS DETECTED BY CELLULAR IMMUNITY TESTS
作者:
NOBUYUKI TANAKA,
MITSUO TAKASUGI,
PAUL TERASAKI,
期刊:
Transplantation
(OVID Available online 1971)
卷期:
Volume 12,
issue 6
页码: 514-518
ISSN:0041-1337
年代: 1971
出版商: OVID
数据来源: OVID
摘要:
Preimmunization which occurs as a result of transfusion and pregnancy is postulated to be responsible for most early kidney transplant failures. A cell-mediated cytotoxicity test was evaluated as an assay of sensitization. Statistically significant higher levels of immunization could be shown in 29 patients who were in the process of rejecting, or who had already rejected, a transplant when compared to 23 patients with functioning kidney transplants, 53 patients on hemodialysis waiting for transplants, and 23 normal persons. The ability of lymphocytes to kill allogeneic target lines in culture may therefore be a method by which presensitization can be detected before transplantation and by which the state of immunity can be monitored after transplantation.
点击下载:
PDF
(350KB)
返 回