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Neurological manifestations of hemorrhagic colitis in the outbreak ofEscherichia coliO157:H7 infection in Japan

 

作者: Shin‐ichiro Hamano,   Youko Nakanishi,   Takahiro Nara,   Takashi Seki,   Tomoko Ohtani,   Tsutomu Oishi,   Kosuke Joh,   Tsuyoshi Oikawa,   Yasuo Muramatsu,   Yoshihiro Ogawa,   Shunji Akashi,  

 

期刊: Acta Pædiatrica  （WILEY Available online 1993）
卷期: Volume 82, issue 5  

页码: 454-458

 

ISSN:0803-5253

 

年代: 1993

 

DOI:10.1111/j.1651-2227.1993.tb12721.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Escherichia coli O157:H7;hemolytic uremic syndrome;hemorrhagic colitis;Shiga‐like toxin;verotoxin

 

数据来源: WILEY

 

摘要:

An outbreak of hemorrhagic colitis associated withEscherichia coliO157:H7 occurred in a kindergarten in Saitama, Japan from September to November, 1990. Seven patients admitted to our hospital showed neurological manifestations: generalized seizures, impaired consciousness, urinary incontinence, gaze nystagmus, phrenic nerve palsy, action tremor and vertigo. Two patients died. On the basis of the clinical courses and laboratory findings of the seven patients and postmortem findings of one case, these neurological symptoms were suspected to be induced by the verotoxin elaborated byEscherichia coliO157:H7.

 

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