α1-Antitrypsin Variants in Different Racial Groups in Malaysia
作者:
Luan Eng Lie-Injo,
J. Ganesan,
A. Herrera,
C.G. Lopez,
期刊:
Human Heredity
(Karger Available online 1978)
卷期:
Volume 28,
issue 1
页码: 37-40
ISSN:0001-5652
年代: 1978
DOI:10.1159/000152928
出版商: S. Karger AG
关键词: α1-Antitrypsin variants;Malaysia;Populations
数据来源: Karger
摘要:
In a study of Malaysians of different racial groups, 1,510 sera (908 from Malays, 371 from Chinese and 231 from Indians) were identified for their protease inhibitor (Pi) types. The gene frequencies for the alleles PiM, PiS and PiX in Malays were, respectively, 0.979, 0.015, and 0.007. In Chinese, the frequencies were 0.981, 0.019 and 0.000, and in Indians they were 0.976, 0.024, and 0.000. It is interesting that the usually rare PiX type is found in appreciable frequency in the Malays. Two different types with unusual behavior and obscure origin were also found.
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