Serum and Red Cell Enzyme Variants in an Amerindian Tribe
作者:
H. Vergnes,
J.C. Quilici,
M. Gherardi,
G. Bejarano,
期刊:
Human Heredity
(Karger Available online 1976)
卷期:
Volume 26,
issue 4
页码: 252-262
ISSN:0001-5652
年代: 1976
DOI:10.1159/000152811
出版商: S. Karger AG
关键词: Red cell isoenzymes;Serum enzymes;Polymorphism;South America;Indians
数据来源: Karger
摘要:
Blood samples from 109 Siriono (Eastern Bolivia) belonging to the Tupi-Guarani group were investigated for enzyme variants in the following systems: glucose-6-phosphate dehydrogenase, phosphogluconate dehydrogenase, adenylate kinase, phosphoglucomutase (locus 1 and 2), acid phosphatases, lactate dehydrogenase, NADH diaphorase, pseudocholinesterase (E1 and E2 locus), and serum alkaline phosphatase. The most relevant observations are: (1) A relative lack of polymorphism, a characteristic feature of the Amerindian populations studied up to now. These data are consistent with the hypothesis of a ‘common ancestral background’ in Indian populations whatever the degree of socio-cultural and linguistic diversity, and the geographical distances. (2) Specific traits due to the frequency of alleles in some systems confer to that tribe a particular position among Amerindians. The effects of genetic drift may be postulated in order to explain the high rate of PGM and 6PGD polymorphism. Furthermore, in that small community, the disappearance of some alleles (pa gene) can plausibly be explained in terms of a balanced influence of mutational and selective press
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