Histomorphological Evaluation of Wound Healing of Rabbit Oviduct after Microsurgical Reanastomosis with the Use of Autologous Fibrin Adhesive, Human Fibrin Adhesive or Poly-Glycolic Acid Suture
作者:
U.S. Weis-Fogh,
H. Pedersen,
E. Schroeder,
S.S Sørensen,
H.P. Olesen,
期刊:
European Surgical Research
(Karger Available online 1993)
卷期:
Volume 25,
issue 5
页码: 278-286
ISSN:0014-312X
年代: 1993
DOI:10.1159/000129290
出版商: S. Karger AG
关键词: Tissue adhesive;Autologous fibrin adhesive;Wound healing;Microsurgery
数据来源: Karger
摘要:
The morphology of the healing process of microsurgical re-anastomosis of the rabbit oviduct with the use of fibrin adhesive, autologous and heterologous, and conventional sutures is described. Both oviducts in 48 rabbits were cut and reanastomoses were performed. The rabbits were killed at different intervals after the operations, ranging from 2 h to 28 days, and the anastomoses were evaluated by histomorphological examination.The autologous fibrin adhesive was absorbed after a week and an uncomplicated healing was observed. Heterologous fibrin adhesive caused a granulomatous inflammation interpreted as an immune reaction of the host to the foreign protein, and conventional suturing resulted in severe tissue damage with an intensive inflammatory reaction.
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