Surface Markers on Lymphocytes from Human Cerebrospinal Fluid
作者:
P.E. Manconi,
D. Zaccheo,
O. Bugiani,
M.F. Fadda,
A. Cadoni,
M.G. Marrosu,
C. Cianchetti,
V. Grifoni,
期刊:
European Neurology
(Karger Available online 1978)
卷期:
Volume 17,
issue 2
页码: 87-91
ISSN:0014-3022
年代: 1978
DOI:10.1159/000114929
出版商: S. Karger AG
关键词: Cerebrospinal fluid;T lymphocytes;Rosettes;IgG Fc receptors;Surface markers
数据来源: Karger
摘要:
Surface markers of cerebrospinal fluid (CSF) cells have been studied in comparison with those of peripheral blood lymphocytes. The great majority (about 95%) of CSF cells bear surface markers of thymus-dependent lymphocytes (E rosettes with uncoated sheep red blood cells), while being devoid of bone-marrow derived cell markers (EAC rosettes with complement-coated red blood cells). In contrast with lymphocytes from peripheral blood, CSF cells form predominantly ‘early’ and ‘sphere’-shaped E rosettes, and bear receptors for the complement-fixing segment of immunoglobulins G. Treatment with concentrated CSF does not affect rosette forming ability of peripheral blood lymp
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