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Studies on the ‘Linear Pattern’ in Renal Glomeruli Demonstrated with Immunofluorescence

 

作者: Hiroshi Kawachi,   Takashi Oite,   Fujio Shimizu,  

 

期刊: Nephron  （Karger Available online 1985）
卷期: Volume 39, issue 1  

页码: 36-39

 

ISSN:1660-8151

 

年代: 1985

 

DOI:10.1159/000183334

 

出版商: S. Karger AG

 

关键词: Linear pattern;Immunofluorescence;Glomerular basement membrane;Antibody activity;Electric charge

 

数据来源: Karger

 

摘要:

We have experimentally induced the ‘linear pattern’ in immunofluorescence: the linear deposition of endogenous immunoglobulin (Ig) along the glomerular basement membrane (GBM) in rats injected with both protamine and nephrotoxic serum. This Ig was demonstrated to have no specific antibody activity against GBM or rabbit serum. Our findings could be of value in the analysis of the mechanism and pathological meaning of the ‘linear pattern’ of endogenous Ig in immunofluor

 

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