首页   按字顺浏览 期刊浏览 卷期浏览 Biological Study of Alcohol Dependence Syndrome with Reference to Ethnic Difference: Re...
Biological Study of Alcohol Dependence Syndrome with Reference to Ethnic Difference: Report of a WHO Collaborative Study

 

作者: Itaru Yamashita,   Tetsuro Ohmori,   Tsukasa Koyama,   Hideki Mori,   Sergey Boyadjive,   Paul Kielholz,   Markus Gastpar,   Dris Moussaoui,   M. Bouzekraoui,   Brij B. Sethi,   Baltazar V. Reyes,   Marat E. Vartanian,   Juan R. Fuente,   G. Allen German,   Nenad Bohacek,   Norman Sartorius,   Peter Morozov,   Leonid L. Prilipko,  

 

期刊: Psychiatry and Clinical Neurosciences  （WILEY Available online 1990）
卷期: Volume 44, issue 1  

页码: 79-84

 

ISSN:1323-1316

 

年代: 1990

 

DOI:10.1111/j.1440-1819.1990.tb00444.x

 

出版商: Blackwell Publishing Ltd

 

关键词: alcoholism;alcohol metabolism;aldehyde dehydrogenase deficiency;ethnic difference

 

数据来源: WILEY

 

摘要:

Summary:Inherited deficiency of acetaldehyde dehydrogenase type I (ALDH‐I) was found in 43% (50/117) of normals, 33% (27/82) of schizophrenics, but only 4% (5/113) of alcoholics among Japanese. The ALDH‐I deficiency was never found, however, in 146 mostly schizophrenic subjects from Europe (Basel, Moscow, Zagreb), Australia (Nedlands), India (Lucknow), Morocco (Casablanca) and Mexico (Mexico City). It was demonstrated that ALDH‐I deficiency produces the flushing syndrome which inhibits the development of drinking habit and alcohol dependence syn

 

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