Acylcarnitine is Low in Cord Blood in Cystic Fibrosis
作者:
J. D. LLOYD‐STILL,
T. BOHAN,
S. HUGHES,
H. U. WESSEL,
期刊:
Acta Pædiatrica
(WILEY Available online 1990)
卷期:
Volume 79,
issue 4
页码: 427-430
ISSN:0803-5253
年代: 1990
DOI:10.1111/j.1651-2227.1990.tb11488.x
出版商: Blackwell Publishing Ltd
关键词: carnitine metabolites;cord blood;cystic fibrosis
数据来源: WILEY
摘要:
ABSTRACT.Carnitine metabolites (total, free, short and long chain) were analyzed in cord blood of cystic fibrosis (n=5), non‐CF siblings (n=7), and controls (n=8). Total acylcarnitine (short and long chain combined) was significantly lower (<0.001) in CF compared to both control groups. Total and free carnitine showed no significant differences between the three groups. These findings are compatible with disturbed fatty acid metabolism in utero and may be related to the increased energy expenditure characteristic of CF infant
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