Correlation Analysis of Relationships between Vitamin-K-Dependent Clotting Factors and Effective Hepatic Blood Flow, Albumin and Other Liver Function Tests
作者:
M. Fujii,
K. Yasunaga,
H. Uchino,
期刊:
Pathophysiology of Haemostasis and Thrombosis
(Karger Available online 1980)
卷期:
Volume 9,
issue 1
页码: 9-14
ISSN:1424-8832
年代: 1980
DOI:10.1159/000214335
出版商: S. Karger AG
关键词: Liver;Liver blood flow;Liver function tests;Blood coagulation factors;Coagulation tests;Normotest;Prothrombin time;Albumin
数据来源: Karger
摘要:
Relationships between Normotest, prothrombin time, albumin, γ-globulin, GPT, and the hepatic fractional clearance of 198Au-colloids as a measure of effective hepatic blood flow were studied by correlation analysis, in 50 patients with liver diseases, including chronic hepatitis or cirrhosis. Simple correlation coefficients were highly significant between Normotest, prothrombin time, albumin, and the heaptic fractional clearance; however, not between GPT or γ-globulin and the other parameters. Further correlation analysis revealed a highly significant partial correlation coefficient between Normotest and albumin and the hepatic clearance; however, not between Normotest and albumin. As effective hepatic blood flow is considered to be proportional to the liver parenchymal volume, the above results indicate that vitamin-K-dependent clotting factors, as well as albumin, reflect the liver cell mas
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