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Humicolactone, A New Bioactive 10-Membered Lactone from the FungusGilmaniella humicola

 

作者: B. Fischer,   H. Anke,   O. Sterner,  

 

期刊: Natural Product Letters  （Taylor Available online 1995）
卷期: Volume 7, issue 4  

页码: 303-308

 

ISSN:1057-5634

 

年代: 1995

 

DOI:10.1080/10575639508043226

 

出版商: Taylor & Francis Group

 

关键词: Fungal metabolite;Gilmaniella humicola;humicolactone;10-membered lactone;mycorrhizins;antimicrobial;cytotoxic

 

数据来源: Taylor

 

摘要:

The biological activities and the structure determination by spectroscopic methods of humicolactone, a new 10-membered lactone possessing antimicrobial and cytotoxic activities isolated from the cultural fluids of the fungusGilmaniella humicola, is reported. The antimicrobial activity of humicolactone was abolished by preincubation with cysteine, suggesting that it is caused by the reactivity of humicolactone.

 

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