An office procedure or intrauterinc aspiration yielded a 99% diagnostic accuracy in 100 patients admitted Tor cither curcttagc or hysterectomy. After correlation with surgical diagnosis, no false-positive or false-negative results were found. The method provides tissue for cell blocks adequate for histologic diagnosis of endometrial adenocarcinoma and its precursors. The major advantage of this technic in comparison with the Gravlee Jet WasherTMis its low cost. Moreover, in this study, it proved to be less painful, superior for cell block preparation, and yielded more satisfactory specimens. As a screening procedure for asymptomatic patients at risk, this intrauterine aspiration technic holds promise and must be evaluated by further studies.